Correction to Di-nor and 17-nor-pimaranes from Icacina trichantha

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Antimicrobial and phytochemical screening of Icacina trichantha

Ethanol and water extracts of Icacina trichantha leaves were screened for their phytochemicals and antimicrobial activity against Escherichia coli, Staphylococcus aureus, streptococcus spp, Candida albicans and Klebsiella pneumonia. The result indicated that alkaloids, tannins, saponins, and phenols were present in the plant part. Both the ethanol extract and the water extract were active again...

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Correction to Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

Herein, we report the first synthesis of a demethylated form of cholesterol (18,19-di-nor-cholesterol), in which the C18 and C19 methyl groups of the β-face were eliminated. Recent molecular simulations modeling 18,19-di-nor-cholesterol have suggested that cholesterol's opposing rough β-face and smooth α-face play necessary roles in cholesterol's membrane condensing abilities and, additionally,...

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Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

Herein, we report the first synthesis of a demethylated form of cholesterol (18,19-di-nor-cholesterol), in which the C18 and C19 methyl groups of the β-face were eliminated. Recent molecular simulations modeling 18,19-di-norcholesterol have suggested that cholesterol’s opposing rough β-face and smooth α-face play necessary roles in cholesterol’s membrane condensing abilities and, additionally, ...

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ژورنال

عنوان ژورنال: Journal of Natural Products

سال: 2016

ISSN: 0163-3864,1520-6025

DOI: 10.1021/acs.jnatprod.6b00837